Hi Powerbiz,
Well you need a domain and web hosting to do things right either way.
Chances are you need a site up that can be reviewed to even get approved by Linkshare and GreatSkin.
Most good hosts that you can get for 9 a month or less should have MSQL database on my server and PHP. But even if you get a domain and free website builder from GoDaddy you still need a hosting account like I mentioned above.
If I were you I would learn a little more before proceeding so you don't go off on a tangent that wont be productive. It sounds like you are possibly rushing in and not clear on some things. I THINK, but am not sure - if you use Popshops you don't even need to deal with MSQL and PHP if you are using the free option. I think all it is, is javascript.
I assume when you mention MSQL and PHP thats referring to what you need to pull and display their product feed? That would require software and programming and also I think Linkshare still charges you to pull a feed.
I think William is the GreatSkin affiliate manager at AMWSO. So contact him
GreatSkin Skin Care Affiliate Program and make sure you know the best options for starting out.